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Postgrad Med 134 , 1419 (2021)
* Cardiorenal Protection: SGLT2 inhibitors and GLP-1 agonists are now strongly recommended for high-risk patients regardless of their current A1c level

Apart from their utility in the management of T2D, injectable liraglutide and semaglutide have gained licences for the management of overweight/obesity in people without T2D at higher doses than used for treatment of T2D

In addition to their dramatic effects on blood sugar control and weight loss, GLP-1 receptor agonists (GLP-1 RAs) , the class of drugs including multi-billion blockbusters such as semaglutide (Ozempic) and tirzepatide (Mounjaro, Zepbound), have shown intriguing benefits beyond metabolism
