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Weight management can be influenced by many non-modifiable factors like genetic predispositions, age, and ethnicity
September 22, 2023

The data is clear that stopping tirzepatide entirely leads to significant weight regain
Most common side effects were gastrointestinal, with 24.5% of participants in the phase 2 obesity trial discontinuing efinopegdutide 10 mg due to AE however when the same dose was used with gradual escalation at the MASLD trial (starting dose 2.4 mg for 4 weeks, then 5 mg for 4 weeks and then 10 mg), only 5.6% of participants discontinued the medication due to AE
