![how does glp 1 help insulin resistance GLP-1-based therapies for type 2 diabetes: from single, dual and triple agonists to endogenous GLP-1 production and L-cell differentiation | Diabetology & Metabolic Syndrome glp-1_analogs [TUSOM | Pharmwiki]](https://media.springernature.com/m685/springer-static/image/art%3A10.1186%2Fs13098-025-01623-w/MediaObjects/13098_2025_1623_Figa_HTML.png)
how does glp 1 help insulin resistance GLP-1-based therapies for type 2 diabetes: from single, dual and triple agonists to endogenous GLP-1 production and L-cell differentiation | Diabetology & Metabolic Syndrome glp-1_analogs [TUSOM | Pharmwiki]
Description
Glucagon-like peptide-1 increases heart rate by a direct action on the sinus node GLP-1 has direct chronotropic effects on the heart mediated by GLP-1 receptors in pacemaker cells of the sinus node, inducing changes in action potential morphology
![how does glp 1 help insulin resistance GLP-1-based therapies for type 2 diabetes: from single, dual and triple agonists to endogenous GLP-1 production and L-cell differentiation | Diabetology & Metabolic Syndrome glp-1_analogs [TUSOM | Pharmwiki]](https://tmedweb.tulane.edu/pharmwiki/lib/exe/fetch.php/glp1.png?w=600&tok=baf39c)
Members of $MED's Scientific and Clinical Affairs team and Medifasts Scientific Advisory Board recently published an article in Diabetes, Obesity and Metabolism, highlighting GLP-1 discontinuation rates
![how does glp 1 help insulin resistance GLP-1-based therapies for type 2 diabetes: from single, dual and triple agonists to endogenous GLP-1 production and L-cell differentiation | Diabetology & Metabolic Syndrome glp-1_analogs [TUSOM | Pharmwiki]](http://www.mygreatlearning.com/blog/wp-content/uploads/2025/12/How-GLP-1-Drives-Weight-Loss-636x1024.png)
Convenient capsule format for consistent daily use
![how does glp 1 help insulin resistance GLP-1-based therapies for type 2 diabetes: from single, dual and triple agonists to endogenous GLP-1 production and L-cell differentiation | Diabetology & Metabolic Syndrome glp-1_analogs [TUSOM | Pharmwiki]](https://www.mdpi.com/ijms/ijms-27-01886/article_deploy/html/images/ijms-27-01886-g003.png)
With the right plan, medical support, and mindset, long-term weight loss results can be maintained.
![how does glp 1 help insulin resistance GLP-1-based therapies for type 2 diabetes: from single, dual and triple agonists to endogenous GLP-1 production and L-cell differentiation | Diabetology & Metabolic Syndrome glp-1_analogs [TUSOM | Pharmwiki]](https://static.wixstatic.com/media/b353a6_0e13e94aec694954920b7c5eca2fd2fa~mv2.png/v1/fill/w_568,h_544,al_c,q_85,usm_0.66_1.00_0.01,enc_avif,quality_auto/b353a6_0e13e94aec694954920b7c5eca2fd2fa~mv2.png)
