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Start with a lower dose than patients reported compounded drug dose and titrate up slowly, Basina said

Its a decision that should be made in partnership with a medical professional who understands the nuances of these powerful medications

Reasonable triggers include: vomiting or diarrhea persisting beyond 24-48 hours, inability to keep down fluids, symptoms of dehydration, muscle weakness interfering with function, or mental status changes
These approaches can make the medication easier to tolerate without reducing its effectiveness
