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Description
Phase 2 trial (NEJM 2023) used a structured ramp to 12 mg/week but at trial doses of 8 mg and 12 mg, dropout from gastrointestinal events was substantial

Mrak RE, Griffin WST

Yes, but the legal pathway has narrowed significantly from 2022-2025

Pink (lighter B12 dose) and red (standard B12 dose) are both within normal range
