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Description
It mimics ghrelin and stimulates the pituitary through a separate pathway

Thus, similar to TLR3 signalling, the TRIF-dependent arm of TLR4 signalling requires ANKIB1 for effective TBK1 activation and downstream IRF3-dependent IFN induction

However, more recent research has revealed that CHAC2 expression is subject to complex regulation and is implicated in diverse cellular processes

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