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Numerous research studies have substantiated that GM significantly influences conditions related to immunity, weight regulation, obesity, and energy homeostasis [7]

This series of pathological alterations further exacerbates local hypoxia and, through the classic hypoxia signaling pathway, stabilizes HIF-1, thereby driving disease progression [102]

Abnormal glucose and insulin metabolism has been implicated in Alzheimer disease as well

For YAP and E-cadherin staining, the number of epithelial cells showing nuclear YAP retention in the villus compartment was counted across ten villi in three non-treat control samples and 5-FU-treated samples