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doi: 10.1126/science.aaz7548 199 WangWGreenMChoiJEGijnMKennedyPDJohnsonJKet al

The change from uncompetitive to non-competitive mechanism induced by chemical modifications of the inhibitors is not rare in drug design studies 48,49,50

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Consequently, diminished GSH undermines the coordinated immune response, disrupting cell-mediated immunity and weakening the ability to combat infections
