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This reduces the levels of glucose and glycated hemoglobin in the plasma of T2DM patients [151], resulting in decreased insulin levels and increased glucagon release, thereby promoting the production of ketones [152]

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We have listed SCFAs-related studies separately ( Table 3 ), which contains two studies in 2023 ( Eisenbergiella , a bacterial genus known for its butyrate-producing capacity ( 3.3.6 Regulatory effects of TCMPs on genes and proteins in gut microbiota-associated pathways Among the nine included studies, we further summarized the pathways through which TCMPs exert therapeutic effects on RA and systematically cataloged the involved genes and proteins ( Table 3 )