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Notably, BBR was found to inhibit the microbial metabolism of tyrosine, thereby suppressing p-cresol production, a process potentially linked to its ability to restrain Clostridium proliferation

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Taken together, these findings support the concept that fecal butyrate may serve as a complementary biomarker of mucosal healing and treatment response, and further position MSB as a promising therapeutic adjunct in UC, warranting continued investigation in larger and longer-term clinical trials

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